چكيده
In this dissertation effective methods for synthesis of 2- amino – 3 – cyano – 7 – hydroxyl – 4 – hydrogen chromenes have been considered through the reaction of knoevenagel and using environmentally friendly catalysts and environmentally friendly low – soluble solvents . In this synthesis method we have also tried to use a one – pot multicomponent reaction that uses aldehydes aromatic, malonnitrile and acidic compounds with reactivable hydrogenated active hydrogen ( resorcinol ) in the preparation of 2 – amino – 4 – hydrogen chromates by ringing formation .In this reaction a few components of environmentally friendly lewis acid catalysts as well as nanoparticles of magnetic α-Fe 2 O 3 , NiZnFe2O4 nanoparticles supported on graphene oxide through amino propyl triethoxycylan (APTES ) were performed and good results were obtained .These catalysts have magnetic properties and are easily separated form the product by a strong external magnet .
Key words : chromenes ,knoevenagle reaction , environmental friendly cataly
