چكيده
In this research work, the reaction of Theophylin drug formation with heavy metal cations such as cadmium, mercury, zinc, etc. in binary solvents of acetonitrile and dimethyl sulfoxide with different ratios was investigated by visible-ultraviolet spectroscopy. The molar ratio method was used to calculate the stoichiometry of the reactions and to determine the constant values of cation complex formation with the drug. The above parameters were calculated using the fitting method of changes in adsorption values in terms of molar ratio using a nonlinear computer program. Due to the formation constants of different drug-cation complexes, the interaction in acetonitrile solvent is stronger. In other words, with decreasing the constant solvent ratio of acetonitrile, the formation of the complex has also decreased, which is correctly related to the solvent yield
